תשפ"א

The years תש"פ and תשפ"א could refer to how we need to cover both our mouths and noses with masks:

תש"פ = תהא שנת פה  (It should be the year of the mouth)

תשפ"א = תהא שנת אף (It should be the year of the nose)

May our הסתר פנים mark the end of Hashem's הסתר פנים.

Alternatively, just spell out the last 2 letters and change the vowels a bit:

תשפ"א = תהא שנת פִּי אֶלֶף (It should be the year of a thousand-fold)

This may refer to President Trump's warning to Iran:

...caused over so many years. Any attack by Iran, in any form, against the United States will be met with an attack on Iran that will be 1,000 times greater in magnitude!

— Donald J. Trump (@realDonaldTrump) September 15, 2020

Or it may refer to this verse:

יא  יְהוָה אֱלֹהֵי אֲבוֹתֵכֶם, יֹסֵף עֲלֵיכֶם כָּכֶם--אֶלֶף פְּעָמִים; וִיבָרֵךְ אֶתְכֶם, כַּאֲשֶׁר דִּבֶּר לָכֶם.

11 The LORD, the God of your fathers, make you a thousand times so many more as ye are, and bless you, as He hath promised you!

In any case, we hope for what is said in אחות קטנה:

אֵל נָא רְפָא נָא לְמַחֲלוֹתֶיהָ

תִּכְלֶה שָׁנָה וְקִלְלוֹתֶיהָ

Please, oh G-d, heal its sicknesses.

Let the year and its curses end.

especially in light of the fact that we mentioned previously that:

רפא נא לה = קורונה.

And may we then say:

תָּחֵל שָׁנָה וּבִרְכוֹתֶיהָ

Let the year and its blessings begin.